PRODUCT DETAILS

About Afinitor 10mg Tablet

EVEROLIMUS belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer, and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

EVEROLIMUS contains 'Everolimus' that belongs to the group of medicines known as 'kinase inhibitors. It works by decreasing the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take EVEROLIMUS as prescribed by your doctor. You are advised to take EVEROLIMUS for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth), and upper respiratory tract infection. Most of these side effects of EVEROLIMUS do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking EVEROLIMUS for as long as your doctor has prescribed. If you are known to be allergic to EVEROLIMUS or any other medicines, please tell your doctor. Do not take EVEROLIMUS if you are pregnant or planning for pregnancy as EVEROLIMUS may harm the unborn baby. EVEROLIMUS should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. EVEROLIMUS causes tiredness, thus, it is advisable to you do not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of Afinitor 10mg Tablet

Breast cancer, pancreatic cancer, lung cancer, and kidney cancer.

Medicinal Benefits of Afinitor 10mg Tablet

EVEROLIMUS is indicated for the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer, and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. EVEROLIMUS travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreasing the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

Directions for Use

EVEROLIMUS can be taken without food but always in the same way either without food or with food. The tablet form of EVEROLIMUS should be swallowed as a whole with an ample amount of water, do not chew or break the tablet. You are advised to take EVEROLIMUS for as long as your doctor has prescribed it for you depending on your medical condition.

Side Effects of Afinitor 10mg Tablet

• Tiredness
• Breathlessness
• Dizziness
• Headache
• Loss of appetite
• Infection
• Mouth ulcers 
• Sinus inflammation
• Cough
• Diarrhea
• Fever
• High level of sugar in the blood (hyperglycemia)
• Signs of low level of red blood cells (anemia) 
• Otitis media (infection of the ear)
• Stomatitis (Inflammation of the mouth)
• Upper respiratory tract infection.
• Swelling of arms, hands, feet, ankles

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are known to be allergic to EVEROLIMUS or any other medicines, please tell your doctor. EVEROLIMUS should not be taken for the conditions like liver disease, diabetes, and high level of cholesterol. Do not take EVEROLIMUS if you have recent surgery, infection, or hepatitis B. EVEROLIMUS may weaken your immune system, inform your doctor before taking EVEROLIMUS. EVEROLIMUS may also impair your kidney function. Therefore, monitor your kidney function regularly while taking EVEROLIMUS. EVEROLIMUS may cause cough, fever, and shortness of breathing, thereby informing your doctor while taking you EVEROLIMUS. EVEROLIMUS may cause skin cancer, if you observe night sweating, weight loss, change in color, and size of mole inform your doctor. Do not take EVEROLIMUS if you are pregnant or planning for pregnancy as EVEROLIMUS may harm the unborn baby. EVEROLIMUS should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. EVEROLIMUS causes tiredness, thus, it is advisable to you do not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug Interactions

Drug-Drug Interaction:

EVEROLIMUS may have interaction with antifungal medicines (ketoconazole, itraconazole, voriconazole, fluconazole), antibiotics (clarithromycin, telithromycin, erythromycin), anti-HIV medicines (ritonavir, efavirenz), blood pressure-lowering medicines (ramipril, verapamil, diltiazem), medicines for heart disease (dronedarone), medicines for decreasing growth of abnormal cells (imatinib), medicines for fits/ epilepsy (phenytoin, carbamazepine, phenobarbital).

Drug-Disease Interaction:

EVEROLIMUS should not be given to patients with liver disease, kidney disease, diabetes, high level of cholesterol, and infections.

Safety Advice

ALCOHOL

You are recommended to avoid alcohol consumption while taking EVEROLIMUS to avoid unpleasant side effects.

PREGNANCY

EVEROLIMUS is belonging to the pregnancy C category. It is not safe in pregnancy as it may cause harm to the unborn baby. Do not conceive a baby while taking EVEROLIMUS.

BREAST FEEDING

EVEROLIMUS should not be taken by breastfeeding mothers as it may harm the new-born baby

DRIVING

EVEROLIMUS may cause tiredness (fatigue), do not drive or operate heavy machinery if you feel dizzy.

LIVER

EVEROLIMUS should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

KIDNEY

EVEROLIMUS is likely unsafe in patients with severe kidney disease as it may cause kidney failure which can be dangerous, use EVEROLIMUS only when prescribed by a doctor.